What’s NMN?
NMN is short for nicotinamide mononucleotide, a naturally sourced molecule present in all species. Around the molecular level, it is just a ribonucleotide, an elementary structural unit with the nucleic acid RNA. It includes a nicotinamide group, a ribose, plus a phosphate group.
NMN is really a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that could be attractive scaling down some facets of aging. NAD+ serves many critical functions in your cells, including electron transport, cell signaling, and DNA repair.
Accumulating evidence shows that as we get older, our levels of NAD+ decline, increasing our likelihood of age-related diseases.
That’s where the NAD+ precursor NMN also comes in. Some researchers believe that as we can restore that lost NAD+, we’re able to not just slow down aging but also delay various age-related diseases. Regardless of whether restoring NAD+ metabolism in humans will decelerate aging or support healthy longevity remains an unanswered question, though the animal data is promising.
What foods contain NMN?
NMN can be found naturally in foods such as avocado, broccoli, cabbage, cucumber, and edamame. This is how much NMN can be found in some common foods.
While these kinds of foods are an excellent source of nutrition, dietary NMN supplements are also available. These supplements typically can be found in doses which is between 100 – 500 mg, although an optimal dose has not determined in people.
Fasting and caloric restriction also appear to increase NAD+ levels and improve the activity of sirtuins, aka the longevity genes. It’s advocated the activity relies on the use of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and it seems to decrease aging.
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