10 Stuff you Couldn’t know About Nicotine

Nicotine, a chemical normally found in the plants with the Solanaceae family, can be an alkaloid which is found accumulated inside the leaves of these plants, although biosynthesis of this chemical happens in the roots with the plants. Nicotine is among the major aspects of addictive plants like tobacco (0.6%-3.0%) which is the grounds behind their addiction in humans due to its psychoactive nature.


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1. Etymology

The name nicotine emanates from the scientific name with the tobacco plant Nicotiana tabacum. The scientific name with the tobacco plant is itself named french ambassador to Portugal Jean Nicot de Villemain. Villeman is credited for sending tobacco seeds and plant saplings to Paris in 1560 for the use within medicinal purposes.

2. Extraction

Nicotine was first taken from the tobacco plant by German physician Dr. Wilhelm Heinrich Posselt and chemist Karl Ludwig Reimann in 1828. After its discovery Posselt and Reimann labelled it a poison. In fact nicotine can be an antiherbivore chemical, that causes addiction when consumed in small amounts (1mg or fewer) and death if consumed high amounts (30mg-60mg).

3. Chemistry

Nicotine can be an alkaloid using the chemical formula C10H14N2. Its IUPAC name is 3[2,5-1-methylpyrrolidin-2-yl]pyridine. It has a molecular mass of 162.12g/mol. Nicotine can be a hygroscopic liquid which is miscible with water as a nitrogenous base. Its density is 1.01g/cm3, melting point -79oC and boiling point 247oC. The nicotine molecule has a half duration of 2 hours and its particular metabolism is hepatic. Nicotine is additionally optically active and contains two enantiomeric forms.

4. Nicotine as a possible insecticide

As already said nicotine can be an antiherbivore drug which if consumed considerable amounts is fatal alive forms. This is why nicotine laden tobacco has been employed as a possible insecticide before the globe War II. But following the WWII its usage drastically lowered as a result of availability of cheap synthetic insecticides that are more easily accessible than tobacco and much less damaging to mammals. But in the present times the hype surrounding organic farming has again increased the eye with the farmers inside the usage of tobacco as a pesticide as a possible alternate to chemical pesticides.

5. Nicotine addiction

Our neurological system has certain nicotinic acetylcholine receptors. Nicotine binds a number of of these and boosts the volume of several neurotransmitters. Of these neurotransmitters dopamine is a such neurotransmitter which is significantly increased during nicotine use which is responsible for the experience of euphoria and relaxation brought on by using tobacco (nicotine) products.

6. Psychoactive outcomes of nicotine

Nicotine can be a psychoactive substance as it is mood altering. It causes both euphoria and relaxation. In your body nicotine is metabolised inside the liver. First after its metabolism nicotine ends in the making of glucose from your liver and epinephrine from your adrenal medulla. This sudden launch of glucose and epinephrine causes euphoria following the consumption of nicotine. Following your initial euphoria nicotine results in relaxation, increased alertness and sharpness by focusing on different neurotransmitters with the body. Nicotine also offers pain relieving properties.

7. Unwanted effects of nicotine intake

Tough it seems like nicotine is a superb substance to raise one’s sharpness, induce calmness and elevate one’s mood there are more negative elements of nicotine intake than positive. Of these the most frequent side effects of nicotine intake are an increased risk of hypertension and cardiac arrest. It really is sad that many cigarette that a man smokes reduces his life span by 14 years. Moreover since nicotine has been seen as to get a new working of Estrogen on hippocampus, hence in the end nicotine users are inclined to amnesia and other associated diseases.

8. Toxicity

Nicotine is recognized as more toxic than most common drugs like heroin and cocaine. More damage is done by nicotine for the human body which is readily absorbed with the bloodstream and reaches the mind from the lungs within 7 seconds of the intake either orally or as the nicotine patch.

9. Usage of nicotine in medical science

Though nicotine is not an doctor’s best friend, it is though not his worst foe. Nicotine famous for its pain relieving properties is being researched upon for use as a potential medication minus its harmful effects. Nicotine has also been found to lessen preeclampsia, allergic asthma; and others by becoming an anti-inflammatory agent.

10. Nicotine in literature

Nicotine has been personified in popular literature as Nick O’ Teen, a humanoid villainous character in Superman comics that has been created as part of anti-nicotine drive to educate children regarding the ill-effects of nicotine intake in any form.
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